Current Delivery Recommendations for Pregnant Women with Genital Herpes Infection

Vaginal delivery is acceptable if there are no active lesions at term in a woman with intact membranes who has had active Herpes Simplex Virus (HSV) lesions during pregnancy.
If there are active lesions at or near to term in a woman who is in labor or who has ruptured membranes, cesarean delivery is strongly recommended.

Newborns delivered through an infected birth canal should be isolated to protect other newborns in the nursery. The mucous membranes (eyes and nasopharynx) of the newborn should only be cultured 24 to 48 hours after delivery to avoid positive cultures resulting from contamination from maternal sources. (ACOG, 1999).